The 1,1,1-Trimethoxy-2-chloroethane, with the CAS registry number 74974-54-2, is also known as Trimethyl (chloromethyl)orthoformate. This chemical's molecular formula is C₅H₁₁ClO₃ and molecular weight is 154.59. What's more, its systematic name is 2-Chloro-1,1,1-trimethoxyethane.

Physical properties of 1,1,1-Trimethoxy-2-chloroethane are: (1)ACD/LogP: 0.916; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.92; (4)ACD/LogD (pH 7.4): 0.92; (5)ACD/BCF (pH 5.5): 2.92; (6)ACD/BCF (pH 7.4): 2.92; (7)ACD/KOC (pH 5.5): 75.01; (8)ACD/KOC (pH 7.4): 75.01; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 27.69 Å²; (13)Index of Refraction: 1.412; (14)Molar Refractivity: 35.264 cm³; (15)Molar Volume: 141.589 cm³; (16)Polarizability: 13.98×10^-24cm³; (17)Surface Tension: 27.29 dyne/cm; (18)Density: 1.092 g/cm³; (19)Flash Point: 40.85 °C; (20)Enthalpy of Vaporization: 36.465 kJ/mol; (21)Boiling Point: 143.215 °C at 760 mmHg; (22)Vapour Pressure: 6.77 mmHg at 25°C.

Preparation: this chemical can be prepared by 1,1,1-trimethoxy-ethane at the temperature of 50 - 60 °C. This reaction will need reagent t-BuOCl and solvent CCl₄ with the reaction time of 15 min. The yield is about 57%.

Uses of 1,1,1-Trimethoxy-2-chloroethane: it can be used to produce 2-chloromethyl-4-nitro-benzooxazole at the temperature of 65 °C. It will need reagent p-TsOH·H₂O and solvent ethanol with the reaction time of 22 hours. The yield is about 69%.

When you are using this chemical, please be cautious about it as the following:
This chemical is flammable, so you should keep it away from sources of ignition - No smoking. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: ClCC(OC)(OC)OC
(2)Std. InChI: InChI=1S/C5H11ClO3/c1-7-5(4-6,8-2)9-3/h4H2,1-3H3
(3)Std. InChIKey: NPEIUNVTLXEOLT-UHFFFAOYSA-N